NJCAA Championship Teams from Region XVI
| Year | College | Sport |
| 1954 | Moberly Area Community College | Men's Basketball |
| 1955 | Moberly Area Community College | Men's Basketball |
| 1966 | Moberly Area Community College | Men's Basketball |
| 1967 | Moberly Area Community College | Men's Basketball |
| 1967 | STLCC - Florissant Valley | Men's Soccer |
| 1969 | STLCC - Florissant Valley | Men's Soccer |
| 1970 | STLCC - Florissant Valley | Men's Soccer |
| 1971 | STLCC - Florissant Valley | Men's Soccer |
| 1972 | STLCC - Florissant Valley | Men's Soccer |
| 1972 | STLCC - Meramec | Baseball |
| 1972 | STLCC - Forest Park | Judo |
| 1973 | STLCC - Forest Park | Judo |
| 1974 | STLCC - Forest Park | Judo |
| 1974 | STLCC - Meramec | Men's Soccer |
| 1975 | STLCC - Florissant Valley | Men's Soccer |
| 1975 | STLCC - Forest Park | Judo |
| 1976 | STLCC - Forest Park | Judo |
| 1976 | STLCC - Florissant Valley | Volleyball |
| 1976 | STLCC - Meramec | Men's Soccer |
| 1979 | Three Rivers Community College | Men's Basketball |
| 1981 | STLCC - Florissant Valley | Men's Soccer |
| 1982 | Moberly Area Community College | Women's Basketball |
| 1984 | STLCC - Florissant Valley | Men's Soccer |
| 1985 | STLCC - Florissant Valley | Men's Soccer |
| 1986 | Crowder Community College | Softball |
| 1988 | STLCC - Florissant Valley | Women's Soccer |
| 1989 | STLCC - Florissant Valley | Men's Soccer |
| 1990 | STLCC - Florissant Valley | Women's Soccer |
| 1991 | STLCC - Meramec | Women's Soccer |
| 1992 | STLCC - Meramec | Women's Soccer |
| 1992 | Three Rivers Community College | Men's Basketball |
| 2006 | Jefferson College | Men's Soccer |
| 2007 | MCC-Longview | Baseball D-II |
| 2019 | Mineral Area College | Men's Cross Country - DIII |
| 2020 | Mineral Area College | Men's Cross Country - DIII |